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NCID > About NCID > Leadership > Associate Professor David Lye

Associate Professor David Lye

Associate Professor David Lye

Dr David Lye.jpg

Infectious Disease Research and Training Office


Clinical interests
Antimicrobial resistance, general and nosocomial infections, bone and joint infections, HIV medicine, tropical infectious diseases

Language(s) spoken
English, Mandarin, Malay, Cantonese


Associate Professor David LYE Chien Boon (MBBS, FRACP, FAMS, FRCP) graduated in medicine on the Dean's List from the University of Melbourne in 1996 and completed specialty training in infectious diseases in Australia in 2004. He returned to Singapore to work at the Department of Infectious Diseases, Tan Tock Seng Hospital (TTSH) in 2005.

He is currently senior consultant, Department of Infectious Diseases, TTSH and associate professor at Yong Loo Lin School of Medicine, National University of Singapore as well as Lee Kong Chian School of Medicine, Nanyang Technological University. At the National Centre for Infectious Diseases, Professor Lye is Director of the Infectious Disease Research and Training Office. At TTSH, he founded and led the Antimicrobial Stewardship Programme from 2009 to 2018. He is the current chair of the National Antimicrobial Stewardship Expert Panel.  He is a member of National Antimicrobial Resistance Control Committee and One Health Antimicrobial Resistance Project Team, Ministry of Health, Singapore.

Professor Lye has held more than SGD$10million in research grant as principal investigator to date. He has published more than 240 peer-reviewed manuscripts in journals such as NEJM, Lancet, JAMA, Lancet Infectious Diseases, Lancet Global Health as well as Science, Science Translational Medicine, Nature Biotechnology and Nature Communications.

He is an associate editor, BMC Infectious Diseases and Scientific Reports; a member of the editorial board, JAC-Antimicrobial Resistance; and a member of the Editorial Advisory Board, Journal Global Antimicrobial Resistance.

Professor Lye is President of the College of Physicians, Singapore and Society of Infectious Disease (Singapore). He is an advocate for HIV prevention as Vice President of Action for AIDS. Internationally, he is on the executive committee of Asia Pacific Society of Clinical Microbiology and Infection, and International Society of Antimicrobial Chemotherapy, and council of International Society of Infectious Diseases.

Professor Lye's awards include: Dean's Award for Teaching Excellence, Yong Loo Lin School of Medicine, National University of Singapore, 2016; National Healthcare Group Team Recognition Award 2017, Silver, Hospital Acquired Infection Elimination Collaborative; and Tan Tock Seng Hospital Milestone Award 2017, Antimicrobial Stewardship Programme.

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