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Research Publications

Research Publications

  • ​ACTIV-3/TICO Bamlanivimab Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Østergaard L, Chang CC, Goodman AL, Chang W, Dewar RL, Gerry NP, Higgs ES, Highbarger H, Murray DD, Murray TA, Natarajan V, Paredes R, Parmar MKB, Phillips AN, Reilly C, Rupert AW, Sharma S, Shaw-Saliba K, Sherman BT, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Davey VJ, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD. Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. Ann Intern Med. 2022 Feb;175(2):234-243. doi: https://doi.org/10.7326/M21-3507

  • ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group. Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial. Lancet Infect Dis. 2022 May;22(5):622-635. doi: 10.1016/S1473-3099(21)00751-9.​

  • ​ACTIV-3/TICO Study Group, Barkauskas C, Mylonakis E, Poulakou G, Young BE, Vock DM, Siegel L, Engen N, Grandits G, Mosaly NR, Vekstein AM, Rogers R, Shehadeh F, Kaczynski M, Mylona EK, Syrigos KN, Rapti V, Lye DC, Hui DS, Leither L, Knowlton KU, Jain MK, Marines-Price R, Osuji A, Overcash JS, Kalomenidis I, Barmparessou Z, Waters M, Zepeda K, Chen P, Torbati S, Kiweewa F, Sebudde N, Almasri E, Hughes A, Bhagani SR, Rodger A, Sandkovsky U, Gottlieb RL, Nnakelu E, Trautner B, Menon V, Lutaakome J, Matthay M, Robinson P, Protopapas K, Koulouris N, Kimuli I, Baduashvili A, Braun DL, Günthard HF, Ramachandruni S, Kidega R, Kim K, Hatlen TJ, Phillips AN, Murray DD, Jensen TO, Padilla ML, Accardi EX, Shaw-Saliba K, Dewar RL, Teitelbaum M, Natarajan V, Laverdure S, Highbarger HC, Rehman MT, Vogel S, Vallée D, Crew P, Atri N, Schechner AJ, Pett S, Hudson F, Badrock J, Touloumi G, Brown SM, Self WH, North CM, Ginde AA, Chang CC, Kelleher A, Nagy-Agren S, Vasudeva S, Looney D, Nguyen HH, Sánchez A, Weintrob AC, Grund B, Sharma S, Reilly CS, Paredes R, Bednarska A, Gerry NP, Babiker AG, Davey VJ, Gelijns AC, Higgs ES, Kan V, Matthews G, Thompson BT, Legenne P, Chandra R, Lane HC, Neaton JD, Lundgren JD. Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial. Ann Intern Med. 2022 Sep;175(9):1266-1274. doi: 10.7326/M22-1503
  • ​ACTIV-3/TICO Study Group, Rogers AJ, Wentworth D, Phillips A, Shaw-Saliba K, Dewar RL, Aggarwal NR, Babiker AG, Chang W, Dharan NJ, Davey VJ, Higgs ES, Gerry N, Ginde AA, Hayanga JWA, Highbarger H, Highbarger JL, Jain MK, Kan V, Kim K, Lallemand P, Leshnower BG, Lutaakome JK, Matthews G, Mourad A, Mylonakis E, Natarajan V, Padilla ML, Pandit LM, Paredes R, Pett S, Ramachandruni S, Rehman MT, Sherman BT, Files DC, Brown SM, Matthay MA, Thompson BT, Neaton JD, Lane HC, Lundgren JD. The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19. Ann Intern Med. 2022 Oct;175(10):1401-1410. doi: 10.7326/M22-0924
  • ​ACTIV-3–Therapeutics for Inpatients with COVID-19 (TICO) Study Group. Tixagevimab-cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial. Lancet Respir Med. 2022 Oct;10(10):972-984. doi: 10.1016/S2213-2600(22)00215-6. Epub 2022 Jul 8. Erratum in: Lancet Respir Med. 2022 Nov 7;: PMID: 35817072
  • ​Alm, E., Broberg, E. K., Connor, T., Hodcroft, E. B., Komissarov, A. B., Maurer-Stroh, S., Melidou, A., Neher, R. A., O'Toole, Á., & Pereyaslov, D. (2020). Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European  Region, January to June 2020. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European  Communicable Disease Bulletin, 25(32). https://doi.org/10.2807/1560-7917.ES.2020.25.32.2001410
  • Amrun, S. N., Lee, C. Y.-P., Lee, B., Fong, S.-W., Young, B. E., Chee, R. S.-L., Yeo, N. K.-W., Torres-Ruesta, A., Carissimo, G., Poh, C. M., Chang, Z. W., Tay, M. Z., Chan, Y.-H., Chen, M. I.-C., Low, J. G.-H., Tambyah, P. A., Kalimuddin, S., Pada, S., Tan, S.-Y., … Ng, L. F. P. (2020). Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity. EBioMedicine, 58. https://doi.org/10.1016/j.ebiom.2020.102911
  • ​​Anderson, D. E., Tan, C. W., Chia, W. N., Young, B. E., Linster, M., Low, J. H., Tan, Y.-J., Chen, M. I.-C., Smith, G. J. D., Leo, Y. S., Lye, D. C., & Wang, L.-F. (2020). Lack of cross-neutralization by SARS patient sera towards SARS-CoV-2. Emerging Microbes & Infections, 9(1), 900–902. https://doi.org/10.1080/22221751.2020.1761267
  • ​Andre C Kalil, Aneesh K Mehta, Thomas F Patterson, Nathaniel Erdmann, Carlos A Gomez, Mamta K Jain et al. Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial. Lancet Resp Med. 2021-12-01;9(12):1365-1376. doi: 10.1016/S2213-2600(21)00384-2
  • ​Andrew Bosworth, Natasha Y Rickett, Xiaofeng Dong, Lisa FP Ng, Isabel García-Dorival, David A Matthews, Tom Fletcher, Michael Jacobs, Emma C Thomson, Miles W Carroll, Julian A Hiscox. Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care. Genome Med. 2021-12-01;13(1):1-18. doi: 10.1186/s13073-020-00811-9
  • ​Anthony T Tan, Joey ME Lim, Nina Le Bert, Kamini Kunasegaran, Adeline Chia, Martin DC Qui, Nicole Tan, Wan Ni Chia, Ruklanthi de Alwis, Ding Ying, Jean XY Sim, Eng Eong Ooi, Lin-Fa Wang, I Mark, Cheng Chen, Barnaby E Young, Li Yang Hsu, Jenny GH Low, David C Lye, Antonio Bertoletti. Rapid measurement of SARS-CoV-2 spike T cells in whole blood from vaccinated and naturally infected individuals The Journal of Clinical Investigation. 2021-09-01;131(17). doi: 10.1172/JCI152379
  • ​Archuleta, S., Cross, G., Somani, J., Lum, L., Santosa, A., Alagha, R. A., Allen, D. M., Ang, A., Beh, D., Chai, L., Chan, S. M., Lim, S. M., Olszyna, D. P., Ong, C., Oon, J., Salada, B. M. A., Smitasin, N., Sun, L., Tambyah, P. A., … Fisher, D. A. (2020). Responding to COVID-19: How an academic infectious diseases division mobilized in Singapore. BMC Medicine, 18(1), 179. https://doi.org/10.1186/s12916-020-01641-7
  • ​Ashokka, B., Loh, M.-H., Tan, C. H., Su, L. L., Young, B. E., Lye, D. C., Biswas, A., Illanes, S. E., & Choolani, M. (2020). Care of the pregnant woman with coronavirus disease 2019 in labor and delivery: Anesthesia, emergency cesarean delivery, differential diagnosis in the acutely ill parturient, care of the newborn, and protection of the healthcare personnel. American Journal of Obstetrics and Gynecology, 223(1), 66-74.e3. https://doi.org/10.1016/j.ajog.2020.04.005

  • Balachander A, Lee B, Biswas SK, Lye DC, Lin RT, Leo YS, Chui P, Ng LF, Renia L. Organ-specific immune response in lethal SARS-CoV-2 infection by deep spatial phenotyping. Clin Transl Immunology. 2022 May 15;11(5):e1384. doi: 10.1002/cti2.1384.​

  • Bauer, D. C., Metke-Jimenez, A., Maurer-Stroh, S., Tiruvayipati, S., Wilson, L. O. W., Jain, Y., Perrin, A., Ebrill, K., Hansen, D. P., & Vasan, S. S. (2020). Interoperable medical data: The missing link for understanding COVID-19. Transboundary and Emerging Diseases. https://doi.org/10.1111/tbed.13892

  • Beh, D. L. L., Ng, D. H. L., Ong, S. W. X., Sutjipto, S., Lee, P. H., Oon, J., Wong, C. S., & Archuleta, S. (n.d.). The Pandemic Academy: Reflections of Infectious Diseases Fellows During COVID-19. Open Forum Infectious Diseases. https://doi.org/10.1093/ofid/ofaa256

  • ​Beigel, J. H., Tomashek, K. M., Dodd, L. E., Mehta, A. K., Zingman, B. S., Kalil, A. C., Hohmann, E., Chu, H. Y., Luetkemeyer, A., Kline, S., Lopez de Castilla, D., Finberg, R. W., Dierberg, K., Tapson, V., Hsieh, L., Patterson, T. F., Paredes, R., Sweeney, D. A., Short, W. R., … Lane, H. C. (2020a). Remdesivir for the Treatment of Covid-19—Preliminary Report. New England Journal of Medicine, 0(0), null. https://doi.org/10.1056/NEJMoa2007764
  • ​Beigel, J. H., Tomashek, K. M., Dodd, L. E., Mehta, A. K., Zingman, B. S., Kalil, A. C., Hohmann, E., Chu, H. Y., Luetkemeyer, A., Kline, S., Lopez de Castilla, D., Finberg, R. W., Dierberg, K., Tapson, V., Hsieh, L., Patterson, T. F., Paredes, R., Sweeney, D. A., Short, W. R., … Lane, H. C. (2020b). Remdesivir for the Treatment of Covid-19—Final Report. The New England Journal of Medicine, 383(19), 1813–1826. https://doi.org/10.1056/NEJMoa2007764
  • ​Ben Abid F, Salah H, Sundararaju S, Dalil L, Abdelwahab AH, Salameh S, Ibrahim EB, Almaslmani MA, Tang P, Perez-Lopez A, Tsui CKM. Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs. Clin Microbiol Infect. 2023 Aug;29(8):1083.e1-1083.e7. doi: 10.1016/j.cmi.2023.04.025. Epub 2023 Apr 26
  • ​Blasiak A, Truong ATL, Wang P, Hooi L, Chye H, Tan SB, You K, Remus A, Allen DM, Chai LYA, Chan CEZ, Lye DCB, Tan GG, Seah SGK, Chow EK, Ho D. IDentif.AI-Omicron: Harnessing an AI-Derived and Disease-Agnostic Platform to Pinpoint Combinatorial Therapies for Clinically Actionable Anti-SARS-CoV-2 Intervention. ACS Nano. 2022 Sep 27;16(9):15141-15154. doi: 10.1021/acsnano.2c06366
  • ​Brito AF, Semenova E, Dudas G, Hassler GW, Kalinich CC, Kraemer MUG, Ho J, Tegally H, Githinji G, Agoti CN, Matkin LE, Whittaker C; Bulgarian SARS-CoV-2 sequencing group; Communicable Diseases Genomics Network (Australia and New Zealand); COVID-19 Impact Project; Danish Covid-19 Genome Consortium; Fiocruz COVID-19 Genomic Surveillance Network; GISAID core curation team; Network for Genomic Surveillance in South Africa (NGS-SA); Swiss SARS-CoV-2 Sequencing Consortium, Howden BP, Sintchenko V, Zuckerman NS, Mor O, Blankenship HM, de Oliveira T, Lin RTP, Siqueira MM, Resende PC, Vasconcelos ATR, Spilki FR, Aguiar RS, Alexiev I, Ivanov IN, Philipova I, Carrington CVF, Sahadeo NSD, Branda B, Gurry C, Maurer-Stroh S, Naidoo D, von Eije KJ, Perkins MD, van Kerkhove M, Hill SC, Sabino EC, Pybus OG, Dye C, Bhatt S, Flaxman S, Suchard MA, Grubaugh ND, Baele G, Faria NR. Global disparities in SARS-CoV-2 genomic surveillance. Nat Commun. 2022 Nov 16;13(1):7003. doi: 10.1038/s41467-022-33713-y
  • ​C-G Wang, Z Li, S Liu, CT Ng, M Marzuki, PS Jeslyn Wong, B Tan, A Lee, CF Hui Lim, P Bifani, Z Fang, JC Ching Wong, YX Setoh, YY Yang, CH Mun, SZ Fiona Phua, WQ Lim, L Lin, AR Cook, H Tanoto, L-C Ng, A Singhal, YW Leong, XJ Loh. N95 respirator decontamination: a study in reusability Materials Today Advances. 2021-09-01;11(N.A):100148. doi: 10.1016/j.mtadv.2021.100148

  • Carissimo, G., Xu, W., Kwok, I., Abdad, M. Y., Chan, Y.-H., Fong, S.-W., Puan, K. J., Lee, C. Y.-P., Yeo, N. K.-W., Amrun, S. N., Chee, R. S.-L., How, W., Chan, S., Fan, B. E., Andiappan, A. K., Lee, B., Rötzschke, O., Young, B. E., Leo, Y.-S., … Ng, L. F. (2020). Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an  early marker for severe COVID-19. Nature Communications, 11(1), 5243. https://doi.org/10.1038/s41467-020-19080-6

  • ​Chan AY, Ting C, Chan LG, Hildon ZJ. "The emotions were like a roller-coaster": a qualitative analysis of e-diary data on healthcare worker resilience and adaptation during the COVID-19 outbreak in Singapore. Hum Resour Health. 2022 Jul 15;20(1):60. doi: 10.1186/s12960-022-00756-7
  • ​Chan CEZ, Seah SGK, Chye H, Massey S, Torres M, Lim APC, Wong SKK, Neo JJY, Wong PS, Lim JH, Loh GSL, Wang D, Boyd-Kirkup JD, Guan S, Thakkar D, Teo GH, Purushotorman K, Hutchinson PE, Young BE, Low JG, MacAry PA, Hentze H, Prativadibhayankara VS, Ethirajulu K, Comer JE, Tseng CK, Barrett ADT, Ingram PJ, Brasel T, Hanson BJ The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody. PLoS One. 2021 Jun 23;16(6):e0253487. doi: 10.1371/journal.pone.0253487. eCollection 2021.
  • ​Chan CEZ, Wong SKK, Yazid NBM, Ng OT, Marimuthu K, Chan M, Howe HS, Leo YS, Leung BP, Vasoo SS, Young BE. Residual Humoral Immunity Sustained Over Decades in a Cohort of Vaccinia-Vaccinated Individuals. J Infect Dis. 2023 Apr 18;227(8):1002-1006. doi: 10.1093/infdis/jiac409.
  • ​Chan HC, Tambyah PA, Tee NWS, Somani J. Return of other respiratory viruses despite the disappearance of influenza during COVID-19 control measures in Singapore. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 2021 Nov;144:104992. doi: 10.1016/j.jcv.2021.104992
  • ​Chan LLY, Anderson DE, Cheng HS, Ivan FX, Chen S, Kang AEZ, Foo R, Gamage AM, Tiew PY, Koh MS, Lee KCH, Nichol K, Pathinayake PS, Chan YL, Yeo TW, Oliver BG, Wark PAB, Liu L, Tan NS, Wang LF, Chotirmall SH. The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi. Nat Commun. 2022 Dec 10;13(1):7635. doi: 10.1038/s41467-022-35253-x
  • ​Chan YH, Fong SW, Poh CM, Carissimo G, Yeo NK, Amrun SN, Goh YS, Lim J, Xu W, Chee RS, Torres-Ruesta A, Lee CY, Tay MZ, Chang ZW, Lee WH, Wang B, Tan SY, Kalimuddin S, Young BE, Leo YS, Wang CI, Lee B, Rötzschke O, Lye DC, Renia L, Ng LFP. Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2. EMBO Mol Med. 2021 Jun 7;13(6):e14045. doi: 10.15252/emmm.202114045. Epub 2021 May 27.
  • ​Chan YH, Young BE, Fong SW, Ding Y, Goh YS, Chee RS, Tan SY, Kalimuddin S, Tambyah PA, Leo YS, Ng LFP, Lye DC, Renia L. Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir. Front Immunol. 2021 Jun 28;12:680188. doi: 10.3389/fimmu.2021.680188. eCollection 2021.
  • ​Chang ZW, Goh YS, Rouers A, Fong SW, Tay MZ, Chavatte JM, Hor PX, Loh CY, Huang Y, Tan YJ, Neo V, Kam IKJ, Yeo NK, Tan EX, Huang D, Wang B, Salleh SNM, Ngoh EZX, Wang CI, Leo YS, Lin RTP, Lye DCB, Young BE, Muthiah M, Ng LFP, Renia L. Third dose of BNT162b2 improves immune response in liver transplant recipients to ancestral strain but not Omicron BA.1 and XBB. Frontiers in immunology. 2023;14(-):1206016. doi: 10.3389/fimmu.2023.1206016 [doi] 1206016
  • ​Charmaine Malenab Manauis, Marvin Loh, Amanda Hui Jun Lim, James Kwan, Han Jie Teo, David Kuan Peng Teng, Shawn Sushilan Vasoo, Yee Sin Leo, Hou Ang. The next wave: key adaptations to operational workflows of National Screening Centre (Singapore) and the emergency department during the COVID-19 pandemic. Int J Emerg Med. 2021-12-01;14(1):1-8. doi: 10.1186/s12245-021-00337-w
  • ​Chau NVV, Nhan LNT, Nguyet LA, Tu NTK, Hong NTT, Man DNH, Ty DTB, Nhu LNT, Yen LM, Khanh TH, Quy DT, Minh NNQ, Ny NTH, Anderson D, Wang LF, van Doorn HR, Hung NT, Thanh TT, Thwaites G, Tan LV, for OUCRU COVID-19 research group.. Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2021 Oct;111:127-129.
  • ​Chee YJ, Fan BE, Young BE, Dalan R, Lye DC. Clinical trials on the pharmacological treatment of long COVID: A systematic review. J Med Virol. 2023 Jan;95(1):e28289. doi: 10.1002/jmv.28289
  • ​Cheng HL, Lim SM, Jia H, Chen MW, Ng SY, Gao X, Somani J, Sengupta S, Tay DMY, Chua PWL, R A, Ling SYH, McBee ME, Young BE, Sikes HD, Preiser PR. Rapid Evaluation of Vaccine Booster Effectiveness against SARS-CoV-2 Variants. Microbiol Spectr. 2022 Oct 26;10(5):e0225722. doi: 10.1128/spectrum.02257-22
  • ​Chew, Q. H., Wei, K. C., Vasoo, S., & Sim, K. (2020). Psychological and Coping Responses of Health Care Workers Toward Emerging Infectious Disease Outbreaks: A Rapid Review and Practical Implications for the COVID-19 Pandemic. The Journal of Clinical Psychiatry, 81(6). https://doi.org/10.4088/JCP.20r13450
  • ​Chew, Q., Wei, K., Vasoo, S., Chua, H., & Sim, K. (2020). Narrative synthesis of psychological and coping responses towards emerging infectious disease outbreaks in the general population: Practical considerations for the COVID-19 pandemic. Singapore Medical Journal. https://doi.org/10.11622/smedj.2020046

  • Chia, P. Y., Coleman, K. K., Tan, Y. K., Ong, S. W. X., Gum, M., Lau, S. K., Lim, X. F., Lim, A. S., Sutjipto, S., Lee, P. H., Son, T. T., Young, B. E., Milton, D. K., Gray, G. C., Schuster, S., Barkham, T., De, P. P., Vasoo, S., Chan, M., … Singapore 2019 Novel Coronavirus Outbreak Research Team. (2020). Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients. Nature Communications, 11(1), 2800. https://doi.org/10.1038/s41467-020-16670-2

  • ​Chia PY, Ong SWX, Chiew CJ, Ang LW, Chavatte JM, Mak TM, Cui L, Kalimuddin S, Chia WN, Tan CW, Chai LYA, Tan SY, Zheng S, Lin RTP, Wang L, Leo YS, Lee VJ, Lye DC, Young BE. Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study. Clin Microbiol Infect. 2022 Apr;28(4):612.e1-612.e7. doi: 10.1016/j.cmi.2021.11.010.
  • Chia, W. N., Tan, C. W., Foo, R., Kang, A. E. Z., Peng, Y., Sivalingam, V., Tiu, C., Ong, X. M., Zhu, F., Young, B. E., Chen, M. I. C., Tan, Y.-J., Lye, D. C., Anderson, D. E., & Wang, L.-F. (2020). Serological differentiation between COVID-19 and SARS infections. Emerging Microbes & Infections, 1–23. https://doi.org/10.1080/22221751.2020.1780951

  • ​Chia WN, Zhu F, Ong SWX, Young BE, Fong SW, Le Bert N, Tan CW, Tiu C, Zhang J, Tan SY, Pada S, Chan YH, Tham CYL, Kunasegaran K, Chen MI, Low JGH, Leo YS, Renia L, Bertoletti A, Ng LFP, Lye DC, Wang LF. Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study. Lancet Microbe. 2021 Mar 23. doi: 10.1016/S2666-5247(21)00025-2. Epub ahead of print. https://doi.org/10.1016/S2666-5247(21)00025-2

  • ​Chia WN, Zhu F, Ong SWX, Young BE, Fong SW, Le Bert N, Tan CW, Tiu C, Zhang J, Tan SY, Pada S, Chan YH, Tham CYL, Kunasegaran K, Chen MI, Low JGH, Leo YS, Renia L, Bertoletti A, Ng LFP, Lye DC, Wang LF. Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study. Lancet Microbe. 2021 Jun;2(6):e240-e249. doi: 10.1016/S2666-5247(21)00025-2. Epub 2021 Mar 23.
  • ​Chia WN, Tan CW, Tan AWK, Young B, Starr TN, Lopez E, Fibriansah G, Barr J, Cheng S, Yeoh AY, Yap WC, Lim BL, Ng TS, Sia WR, Zhu F, Chen S, Zhang J, Kwek MSS, Greaney AJ, Chen M, Au GG, Paradkar PN, Peiris M, Chung AW, Bloom JD, Lye D, Lok S, Wang LF. Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor. Science advances. 2023 Jul 28;9(30):eade3470. doi: 10.1126/sciadv.ade3470 [doi] eade3470
  • ​Chiew CJ, Premikha M, Chong CY, Wei WE, Ong B, Lye DC, Heng D, Lee VJ, Tan KB. Effectiveness of primary series and booster vaccination against SARS-CoV-2 infection and hospitalisation among adolescents aged 12-17 years in Singapore: a national cohort study. Lancet Infect Dis. 2023 Feb;23(2):177-182. doi: 10.1016/S1473-3099(22)00573-4. Epub 2022 Sep 28
  • ​Chin Chun Ooi, Ady Suwardi, Zhong Liang Ou Yang, George Xu, Chee Kiang Ivan Tan, Dan Daniel, Hongying Li, Zhengwei Ge, Fong Yew Leong, Kalisvar Marimuthu, Oon Tek Ng, Shin Bin Lim, Peter Lim, Wai Siong Mak, Wun Chet Davy Cheong, Xian Jun Loh, Chang Wei Kang, Keng Hui Lim. Risk assessment of airborne COVID-19 exposure in social settings Physics of Fluids. 2021-08-20;33(8):087118.

  • ​Chioh FWJ, Fong SW, Young BE, Wu KX, Krishnan S, Chan YH, Teo LLY, Gao F, Tan RS, Zhong L, Koh AS, Tan SY, Tambyah PA, Renia L, Ng LFP, Lye DC, Cheung C. Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation. Elife. 2021 Mar 23;10:e64909. https://doi.org/10.7554/eLife.64909

  • ​Chow A, Guo H, Kyaw WM, Li AL, Lim RHF, Ang B. Rostered routine testing for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare personnel-Is there a role in a tertiary-care hospital with enhanced infection prevention and control measures and robust sickness-surveillance systems? Infect Control Hosp Epidemiol. 2022 Oct;43(10):1528-1530. doi: 10.1017/ice.2021.268

  • ​Chow A, Htun HL, Kyaw WM, Ang H, Tan G, Tan HN, Koh LW, Thong BY, Ang B. Atypical COVID-19: Preventing transmission from unexpected cases. Infection control and hospital epidemiology. 2021 Sep;42(9):1146-1148. doi: 10.1017/ice.2020.419

  • Choy, C. Y., & Wong, C. S. (2020). It's not all about COVID-19: Pneumocystis pneumonia in the era of a respiratory outbreak. Journal of the International AIDS Society, 23(6), e25533. https://doi.org/10.1002/jia2.25533
  • ​Chye H, Chew CWY, Yeo HP, Tambyah PA, Young BE, Tan GGY, Tan BH, Vasoo S, Chan CEZ. Neutralization escape of emerging subvariants XBB.1.5/1.9.1 and XBB.2.3 from current therapeutic monoclonal antibodies. Journal of medical virology. 2023 Sep;95(9):e29074. doi: 10.1002/jmv.29074
  • ​Clara Chong Hui Ong, Sharifah Farhanah, Kyaw Zaw Linn, Ying Wei Tang, Chu Ying Poon, Allie Yin Lim, Hui Ru Tan, Nur Hafizah Binte Hamed, Xiaowei Huan, Ser Hon Puah, Benjamin CH Ho, Margaret ML Soon, Brenda SP Ang, Shawn Vasoo, Monica Chan, Yee Sin Leo, Oon Tek Ng, Kalisvar Marimuthu. Nosocomial infections among COVID-19 patients: an analysis of intensive care unit surveillance data. Antimicrob Resist Infect Control. 2021-12-01;10(1):1-5. doi: 10.1186/s13756-021-00988-7
  • ​Dalan, R., Ang, L. W., Tan, W. Y. T., Fong, S.-W., Tay, W. C., Chan, Y.-H., Renia, L., Ng, L. F. P., Lye, D. C., Chew, D. E. K., & Young, B. E. (2020). The association of hypertension and diabetes pharmacotherapy with COVID-19 severity  and immune signatures: An observational study. European Heart Journal. Cardiovascular Pharmacotherapy. https://doi.org/10.1093/ehjcvp/pvaa098
  • ​Dalan R, Ang LW, Tan WYT, Fong SW, Tay WC, Chan YH, Renia L, Ng LFP, Lye DC, Chew DEK, Young BE. The association of hypertension and diabetes pharmacotherapy with COVID-19 severity and immune signatures: an observational study. Eur Heart J Cardiovasc Pharmacother. 2021 May 23;7(3):e48-e51. doi: 10.1093/ehjcvp/pvaa098.
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