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ACTIV-3/TICO Bamlanivimab Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Østergaard L, Chang CC, Goodman AL, Chang W, Dewar RL, Gerry NP, Higgs ES, Highbarger H, Murray DD, Murray TA, Natarajan V, Paredes R, Parmar MKB, Phillips AN, Reilly C, Rupert AW, Sharma S, Shaw-Saliba K, Sherman BT, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Davey VJ, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD. Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. Ann Intern Med. 2022 Feb;175(2):234-243. doi: https://doi.org/10.7326/M21-3507
ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group. Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial. Lancet Infect Dis. 2022 May;22(5):622-635. doi: 10.1016/S1473-3099(21)00751-9.
ACTIV-3/TICO Study Group, Barkauskas C, Mylonakis E, Poulakou G, Young BE, Vock DM, Siegel L, Engen N, Grandits G, Mosaly NR, Vekstein AM, Rogers R, Shehadeh F, Kaczynski M, Mylona EK, Syrigos KN, Rapti V, Lye DC, Hui DS, Leither L, Knowlton KU, Jain MK, Marines-Price R, Osuji A, Overcash JS, Kalomenidis I, Barmparessou Z, Waters M, Zepeda K, Chen P, Torbati S, Kiweewa F, Sebudde N, Almasri E, Hughes A, Bhagani SR, Rodger A, Sandkovsky U, Gottlieb RL, Nnakelu E, Trautner B, Menon V, Lutaakome J, Matthay M, Robinson P, Protopapas K, Koulouris N, Kimuli I, Baduashvili A, Braun DL, Günthard HF, Ramachandruni S, Kidega R, Kim K, Hatlen TJ, Phillips AN, Murray DD, Jensen TO, Padilla ML, Accardi EX, Shaw-Saliba K, Dewar RL, Teitelbaum M, Natarajan V, Laverdure S, Highbarger HC, Rehman MT, Vogel S, Vallée D, Crew P, Atri N, Schechner AJ, Pett S, Hudson F, Badrock J, Touloumi G, Brown SM, Self WH, North CM, Ginde AA, Chang CC, Kelleher A, Nagy-Agren S, Vasudeva S, Looney D, Nguyen HH, Sánchez A, Weintrob AC, Grund B, Sharma S, Reilly CS, Paredes R, Bednarska A, Gerry NP, Babiker AG, Davey VJ, Gelijns AC, Higgs ES, Kan V, Matthews G, Thompson BT, Legenne P, Chandra R, Lane HC, Neaton JD, Lundgren JD. Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial. Ann Intern Med. 2022 Sep;175(9):1266-1274. doi: 10.7326/M22-1503
ACTIV-3/TICO Study Group, Rogers AJ, Wentworth D, Phillips A, Shaw-Saliba K, Dewar RL, Aggarwal NR, Babiker AG, Chang W, Dharan NJ, Davey VJ, Higgs ES, Gerry N, Ginde AA, Hayanga JWA, Highbarger H, Highbarger JL, Jain MK, Kan V, Kim K, Lallemand P, Leshnower BG, Lutaakome JK, Matthews G, Mourad A, Mylonakis E, Natarajan V, Padilla ML, Pandit LM, Paredes R, Pett S, Ramachandruni S, Rehman MT, Sherman BT, Files DC, Brown SM, Matthay MA, Thompson BT, Neaton JD, Lane HC, Lundgren JD. The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19. Ann Intern Med. 2022 Oct;175(10):1401-1410. doi: 10.7326/M22-0924
ACTIV-3–Therapeutics for Inpatients with COVID-19 (TICO) Study Group. Tixagevimab-cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial. Lancet Respir Med. 2022 Oct;10(10):972-984. doi: 10.1016/S2213-2600(22)00215-6. Epub 2022 Jul 8. Erratum in: Lancet Respir Med. 2022 Nov 7;: PMID: 35817072
Alm, E., Broberg, E. K., Connor, T., Hodcroft, E. B., Komissarov, A. B., Maurer-Stroh, S., Melidou, A., Neher, R. A., O'Toole, Á., & Pereyaslov, D. (2020). Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin, 25(32). https://doi.org/10.2807/1560-7917.ES.2020.25.32.2001410
Amrun, S. N., Lee, C. Y.-P., Lee, B., Fong, S.-W., Young, B. E., Chee, R. S.-L., Yeo, N. K.-W., Torres-Ruesta, A., Carissimo, G., Poh, C. M., Chang, Z. W., Tay, M. Z., Chan, Y.-H., Chen, M. I.-C., Low, J. G.-H., Tambyah, P. A., Kalimuddin, S., Pada, S., Tan, S.-Y., … Ng, L. F. P. (2020). Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity. EBioMedicine, 58. https://doi.org/10.1016/j.ebiom.2020.102911
Anderson, D. E., Tan, C. W., Chia, W. N., Young, B. E., Linster, M., Low, J. H., Tan, Y.-J., Chen, M. I.-C., Smith, G. J. D., Leo, Y. S., Lye, D. C., & Wang, L.-F. (2020). Lack of cross-neutralization by SARS patient sera towards SARS-CoV-2. Emerging Microbes & Infections, 9(1), 900–902. https://doi.org/10.1080/22221751.2020.1761267
Andre C Kalil, Aneesh K Mehta, Thomas F Patterson, Nathaniel Erdmann, Carlos A Gomez, Mamta K Jain et al. Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial. Lancet Resp Med. 2021-12-01;9(12):1365-1376. doi: 10.1016/S2213-2600(21)00384-2
Andrew Bosworth, Natasha Y Rickett, Xiaofeng Dong, Lisa FP Ng, Isabel García-Dorival, David A Matthews, Tom Fletcher, Michael Jacobs, Emma C Thomson, Miles W Carroll, Julian A Hiscox. Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care. Genome Med. 2021-12-01;13(1):1-18. doi: 10.1186/s13073-020-00811-9
Anthony T Tan, Joey ME Lim, Nina Le Bert, Kamini Kunasegaran, Adeline Chia, Martin DC Qui, Nicole Tan, Wan Ni Chia, Ruklanthi de Alwis, Ding Ying, Jean XY Sim, Eng Eong Ooi, Lin-Fa Wang, I Mark, Cheng Chen, Barnaby E Young, Li Yang Hsu, Jenny GH Low, David C Lye, Antonio Bertoletti. Rapid measurement of SARS-CoV-2 spike T cells in whole blood from vaccinated and naturally infected individuals The Journal of Clinical Investigation. 2021-09-01;131(17). doi: 10.1172/JCI152379
Archuleta, S., Cross, G., Somani, J., Lum, L., Santosa, A., Alagha, R. A., Allen, D. M., Ang, A., Beh, D., Chai, L., Chan, S. M., Lim, S. M., Olszyna, D. P., Ong, C., Oon, J., Salada, B. M. A., Smitasin, N., Sun, L., Tambyah, P. A., … Fisher, D. A. (2020). Responding to COVID-19: How an academic infectious diseases division mobilized in Singapore. BMC Medicine, 18(1), 179. https://doi.org/10.1186/s12916-020-01641-7
Ashokka, B., Loh, M.-H., Tan, C. H., Su, L. L., Young, B. E., Lye, D. C., Biswas, A., Illanes, S. E., & Choolani, M. (2020). Care of the pregnant woman with coronavirus disease 2019 in labor and delivery: Anesthesia, emergency cesarean delivery, differential diagnosis in the acutely ill parturient, care of the newborn, and protection of the healthcare personnel. American Journal of Obstetrics and Gynecology, 223(1), 66-74.e3. https://doi.org/10.1016/j.ajog.2020.04.005
Balachander A, Lee B, Biswas SK, Lye DC, Lin RT, Leo YS, Chui P, Ng LF, Renia L. Organ-specific immune response in lethal SARS-CoV-2 infection by deep spatial phenotyping. Clin Transl Immunology. 2022 May 15;11(5):e1384. doi: 10.1002/cti2.1384.
Bauer, D. C., Metke-Jimenez, A., Maurer-Stroh, S., Tiruvayipati, S., Wilson, L. O. W., Jain, Y., Perrin, A., Ebrill, K., Hansen, D. P., & Vasan, S. S. (2020). Interoperable medical data: The missing link for understanding COVID-19. Transboundary and Emerging Diseases. https://doi.org/10.1111/tbed.13892
Beh, D. L. L., Ng, D. H. L., Ong, S. W. X., Sutjipto, S., Lee, P. H., Oon, J., Wong, C. S., & Archuleta, S. (n.d.). The Pandemic Academy: Reflections of Infectious Diseases Fellows During COVID-19. Open Forum Infectious Diseases. https://doi.org/10.1093/ofid/ofaa256
Beigel, J. H., Tomashek, K. M., Dodd, L. E., Mehta, A. K., Zingman, B. S., Kalil, A. C., Hohmann, E., Chu, H. Y., Luetkemeyer, A., Kline, S., Lopez de Castilla, D., Finberg, R. W., Dierberg, K., Tapson, V., Hsieh, L., Patterson, T. F., Paredes, R., Sweeney, D. A., Short, W. R., … Lane, H. C. (2020a). Remdesivir for the Treatment of Covid-19—Preliminary Report. New England Journal of Medicine, 0(0), null. https://doi.org/10.1056/NEJMoa2007764
Beigel, J. H., Tomashek, K. M., Dodd, L. E., Mehta, A. K., Zingman, B. S., Kalil, A. C., Hohmann, E., Chu, H. Y., Luetkemeyer, A., Kline, S., Lopez de Castilla, D., Finberg, R. W., Dierberg, K., Tapson, V., Hsieh, L., Patterson, T. F., Paredes, R., Sweeney, D. A., Short, W. R., … Lane, H. C. (2020b). Remdesivir for the Treatment of Covid-19—Final Report. The New England Journal of Medicine, 383(19), 1813–1826. https://doi.org/10.1056/NEJMoa2007764
Ben Abid F, Salah H, Sundararaju S, Dalil L, Abdelwahab AH, Salameh S, Ibrahim EB, Almaslmani MA, Tang P, Perez-Lopez A, Tsui CKM. Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs. Clin Microbiol Infect. 2023 Aug;29(8):1083.e1-1083.e7. doi: 10.1016/j.cmi.2023.04.025. Epub 2023 Apr 26
Blasiak A, Truong ATL, Wang P, Hooi L, Chye H, Tan SB, You K, Remus A, Allen DM, Chai LYA, Chan CEZ, Lye DCB, Tan GG, Seah SGK, Chow EK, Ho D. IDentif.AI-Omicron: Harnessing an AI-Derived and Disease-Agnostic Platform to Pinpoint Combinatorial Therapies for Clinically Actionable Anti-SARS-CoV-2 Intervention. ACS Nano. 2022 Sep 27;16(9):15141-15154. doi: 10.1021/acsnano.2c06366
Brito AF, Semenova E, Dudas G, Hassler GW, Kalinich CC, Kraemer MUG, Ho J, Tegally H, Githinji G, Agoti CN, Matkin LE, Whittaker C; Bulgarian SARS-CoV-2 sequencing group; Communicable Diseases Genomics Network (Australia and New Zealand); COVID-19 Impact Project; Danish Covid-19 Genome Consortium; Fiocruz COVID-19 Genomic Surveillance Network; GISAID core curation team; Network for Genomic Surveillance in South Africa (NGS-SA); Swiss SARS-CoV-2 Sequencing Consortium, Howden BP, Sintchenko V, Zuckerman NS, Mor O, Blankenship HM, de Oliveira T, Lin RTP, Siqueira MM, Resende PC, Vasconcelos ATR, Spilki FR, Aguiar RS, Alexiev I, Ivanov IN, Philipova I, Carrington CVF, Sahadeo NSD, Branda B, Gurry C, Maurer-Stroh S, Naidoo D, von Eije KJ, Perkins MD, van Kerkhove M, Hill SC, Sabino EC, Pybus OG, Dye C, Bhatt S, Flaxman S, Suchard MA, Grubaugh ND, Baele G, Faria NR. Global disparities in SARS-CoV-2 genomic surveillance. Nat Commun. 2022 Nov 16;13(1):7003. doi: 10.1038/s41467-022-33713-y
C-G Wang, Z Li, S Liu, CT Ng, M Marzuki, PS Jeslyn Wong, B Tan, A Lee, CF Hui Lim, P Bifani, Z Fang, JC Ching Wong, YX Setoh, YY Yang, CH Mun, SZ Fiona Phua, WQ Lim, L Lin, AR Cook, H Tanoto, L-C Ng, A Singhal, YW Leong, XJ Loh. N95 respirator decontamination: a study in reusability Materials Today Advances. 2021-09-01;11(N.A):100148. doi: 10.1016/j.mtadv.2021.100148
Carissimo, G., Xu, W., Kwok, I., Abdad, M. Y., Chan, Y.-H., Fong, S.-W., Puan, K. J., Lee, C. Y.-P., Yeo, N. K.-W., Amrun, S. N., Chee, R. S.-L., How, W., Chan, S., Fan, B. E., Andiappan, A. K., Lee, B., Rötzschke, O., Young, B. E., Leo, Y.-S., … Ng, L. F. (2020). Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19. Nature Communications, 11(1), 5243. https://doi.org/10.1038/s41467-020-19080-6
Chan AY, Ting C, Chan LG, Hildon ZJ. "The emotions were like a roller-coaster": a qualitative analysis of e-diary data on healthcare worker resilience and adaptation during the COVID-19 outbreak in Singapore. Hum Resour Health. 2022 Jul 15;20(1):60. doi: 10.1186/s12960-022-00756-7
Chan CEZ, Seah SGK, Chye H, Massey S, Torres M, Lim APC, Wong SKK, Neo JJY, Wong PS, Lim JH, Loh GSL, Wang D, Boyd-Kirkup JD, Guan S, Thakkar D, Teo GH, Purushotorman K, Hutchinson PE, Young BE, Low JG, MacAry PA, Hentze H, Prativadibhayankara VS, Ethirajulu K, Comer JE, Tseng CK, Barrett ADT, Ingram PJ, Brasel T, Hanson BJ The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody. PLoS One. 2021 Jun 23;16(6):e0253487. doi: 10.1371/journal.pone.0253487. eCollection 2021.
Chan CEZ, Wong SKK, Yazid NBM, Ng OT, Marimuthu K, Chan M, Howe HS, Leo YS, Leung BP, Vasoo SS, Young BE. Residual Humoral Immunity Sustained Over Decades in a Cohort of Vaccinia-Vaccinated Individuals. J Infect Dis. 2023 Apr 18;227(8):1002-1006. doi: 10.1093/infdis/jiac409.
Chan HC, Tambyah PA, Tee NWS, Somani J. Return of other respiratory viruses despite the disappearance of influenza during COVID-19 control measures in Singapore. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 2021 Nov;144:104992. doi: 10.1016/j.jcv.2021.104992
Chan LLY, Anderson DE, Cheng HS, Ivan FX, Chen S, Kang AEZ, Foo R, Gamage AM, Tiew PY, Koh MS, Lee KCH, Nichol K, Pathinayake PS, Chan YL, Yeo TW, Oliver BG, Wark PAB, Liu L, Tan NS, Wang LF, Chotirmall SH. The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi. Nat Commun. 2022 Dec 10;13(1):7635. doi: 10.1038/s41467-022-35253-x
Chan YH, Fong SW, Poh CM, Carissimo G, Yeo NK, Amrun SN, Goh YS, Lim J, Xu W, Chee RS, Torres-Ruesta A, Lee CY, Tay MZ, Chang ZW, Lee WH, Wang B, Tan SY, Kalimuddin S, Young BE, Leo YS, Wang CI, Lee B, Rötzschke O, Lye DC, Renia L, Ng LFP. Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2. EMBO Mol Med. 2021 Jun 7;13(6):e14045. doi: 10.15252/emmm.202114045. Epub 2021 May 27.
Chan YH, Young BE, Fong SW, Ding Y, Goh YS, Chee RS, Tan SY, Kalimuddin S, Tambyah PA, Leo YS, Ng LFP, Lye DC, Renia L. Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir. Front Immunol. 2021 Jun 28;12:680188. doi: 10.3389/fimmu.2021.680188. eCollection 2021.
Chang ZW, Goh YS, Rouers A, Fong SW, Tay MZ, Chavatte JM, Hor PX, Loh CY, Huang Y, Tan YJ, Neo V, Kam IKJ, Yeo NK, Tan EX, Huang D, Wang B, Salleh SNM, Ngoh EZX, Wang CI, Leo YS, Lin RTP, Lye DCB, Young BE, Muthiah M, Ng LFP, Renia L. Third dose of BNT162b2 improves immune response in liver transplant recipients to ancestral strain but not Omicron BA.1 and XBB. Frontiers in immunology. 2023;14(-):1206016. doi: 10.3389/fimmu.2023.1206016 [doi] 1206016
Charmaine Malenab Manauis, Marvin Loh, Amanda Hui Jun Lim, James Kwan, Han Jie Teo, David Kuan Peng Teng, Shawn Sushilan Vasoo, Yee Sin Leo, Hou Ang. The next wave: key adaptations to operational workflows of National Screening Centre (Singapore) and the emergency department during the COVID-19 pandemic. Int J Emerg Med. 2021-12-01;14(1):1-8. doi: 10.1186/s12245-021-00337-w
Chau NVV, Nhan LNT, Nguyet LA, Tu NTK, Hong NTT, Man DNH, Ty DTB, Nhu LNT, Yen LM, Khanh TH, Quy DT, Minh NNQ, Ny NTH, Anderson D, Wang LF, van Doorn HR, Hung NT, Thanh TT, Thwaites G, Tan LV, for OUCRU COVID-19 research group.. Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2021 Oct;111:127-129.
Chee YJ, Fan BE, Young BE, Dalan R, Lye DC. Clinical trials on the pharmacological treatment of long COVID: A systematic review. J Med Virol. 2023 Jan;95(1):e28289. doi: 10.1002/jmv.28289
Cheng HL, Lim SM, Jia H, Chen MW, Ng SY, Gao X, Somani J, Sengupta S, Tay DMY, Chua PWL, R A, Ling SYH, McBee ME, Young BE, Sikes HD, Preiser PR. Rapid Evaluation of Vaccine Booster Effectiveness against SARS-CoV-2 Variants. Microbiol Spectr. 2022 Oct 26;10(5):e0225722. doi: 10.1128/spectrum.02257-22
Chew, Q. H., Wei, K. C., Vasoo, S., & Sim, K. (2020). Psychological and Coping Responses of Health Care Workers Toward Emerging Infectious Disease Outbreaks: A Rapid Review and Practical Implications for the COVID-19 Pandemic. The Journal of Clinical Psychiatry, 81(6). https://doi.org/10.4088/JCP.20r13450
Chew, Q., Wei, K., Vasoo, S., Chua, H., & Sim, K. (2020). Narrative synthesis of psychological and coping responses towards emerging infectious disease outbreaks in the general population: Practical considerations for the COVID-19 pandemic. Singapore Medical Journal. https://doi.org/10.11622/smedj.2020046
Chia, P. Y., Coleman, K. K., Tan, Y. K., Ong, S. W. X., Gum, M., Lau, S. K., Lim, X. F., Lim, A. S., Sutjipto, S., Lee, P. H., Son, T. T., Young, B. E., Milton, D. K., Gray, G. C., Schuster, S., Barkham, T., De, P. P., Vasoo, S., Chan, M., … Singapore 2019 Novel Coronavirus Outbreak Research Team. (2020). Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients. Nature Communications, 11(1), 2800. https://doi.org/10.1038/s41467-020-16670-2
Chia PY, Ong SWX, Chiew CJ, Ang LW, Chavatte JM, Mak TM, Cui L, Kalimuddin S, Chia WN, Tan CW, Chai LYA, Tan SY, Zheng S, Lin RTP, Wang L, Leo YS, Lee VJ, Lye DC, Young BE. Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study. Clin Microbiol Infect. 2022 Apr;28(4):612.e1-612.e7. doi: 10.1016/j.cmi.2021.11.010.
Chia, W. N., Tan, C. W., Foo, R., Kang, A. E. Z., Peng, Y., Sivalingam, V., Tiu, C., Ong, X. M., Zhu, F., Young, B. E., Chen, M. I. C., Tan, Y.-J., Lye, D. C., Anderson, D. E., & Wang, L.-F. (2020). Serological differentiation between COVID-19 and SARS infections. Emerging Microbes & Infections, 1–23. https://doi.org/10.1080/22221751.2020.1780951
Chia WN, Zhu F, Ong SWX, Young BE, Fong SW, Le Bert N, Tan CW, Tiu C, Zhang J, Tan SY, Pada S, Chan YH, Tham CYL, Kunasegaran K, Chen MI, Low JGH, Leo YS, Renia L, Bertoletti A, Ng LFP, Lye DC, Wang LF. Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study. Lancet Microbe. 2021 Mar 23. doi: 10.1016/S2666-5247(21)00025-2. Epub ahead of print. https://doi.org/10.1016/S2666-5247(21)00025-2
Chia WN, Zhu F, Ong SWX, Young BE, Fong SW, Le Bert N, Tan CW, Tiu C, Zhang J, Tan SY, Pada S, Chan YH, Tham CYL, Kunasegaran K, Chen MI, Low JGH, Leo YS, Renia L, Bertoletti A, Ng LFP, Lye DC, Wang LF. Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study. Lancet Microbe. 2021 Jun;2(6):e240-e249. doi: 10.1016/S2666-5247(21)00025-2. Epub 2021 Mar 23.
Chia WN, Tan CW, Tan AWK, Young B, Starr TN, Lopez E, Fibriansah G, Barr J, Cheng S, Yeoh AY, Yap WC, Lim BL, Ng TS, Sia WR, Zhu F, Chen S, Zhang J, Kwek MSS, Greaney AJ, Chen M, Au GG, Paradkar PN, Peiris M, Chung AW, Bloom JD, Lye D, Lok S, Wang LF. Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor. Science advances. 2023 Jul 28;9(30):eade3470. doi: 10.1126/sciadv.ade3470 [doi] eade3470
Chiew CJ, Premikha M, Chong CY, Wei WE, Ong B, Lye DC, Heng D, Lee VJ, Tan KB. Effectiveness of primary series and booster vaccination against SARS-CoV-2 infection and hospitalisation among adolescents aged 12-17 years in Singapore: a national cohort study. Lancet Infect Dis. 2023 Feb;23(2):177-182. doi: 10.1016/S1473-3099(22)00573-4. Epub 2022 Sep 28
Chin Chun Ooi, Ady Suwardi, Zhong Liang Ou Yang, George Xu, Chee Kiang Ivan Tan, Dan Daniel, Hongying Li, Zhengwei Ge, Fong Yew Leong, Kalisvar Marimuthu, Oon Tek Ng, Shin Bin Lim, Peter Lim, Wai Siong Mak, Wun Chet Davy Cheong, Xian Jun Loh, Chang Wei Kang, Keng Hui Lim. Risk assessment of airborne COVID-19 exposure in social settings Physics of Fluids. 2021-08-20;33(8):087118.
Chioh FWJ, Fong SW, Young BE, Wu KX, Krishnan S, Chan YH, Teo LLY, Gao F, Tan RS, Zhong L, Koh AS, Tan SY, Tambyah PA, Renia L, Ng LFP, Lye DC, Cheung C. Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation. Elife. 2021 Mar 23;10:e64909. https://doi.org/10.7554/eLife.64909.
Chong C, Wee LE, Jin X, Zhang M, Malek MIA, Ong B, Lye D, Chiew CJ, Tan KB. Risks of SARS-CoV-2 JN.1 Infection and COVID-19-Associated Emergency Department Visits/Hospitalizations Following Updated Boosters and Prior Infection: A Population-Based Cohort Study. Clin Infect Dis. 2024 Nov 22;79(5):1190-1196. doi: 10.1093/cid/ciae339.
Chow A, Guo H, Kyaw WM, Li AL, Lim RHF, Ang B. Rostered routine testing for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare personnel-Is there a role in a tertiary-care hospital with enhanced infection prevention and control measures and robust sickness-surveillance systems? Infect Control Hosp Epidemiol. 2022 Oct;43(10):1528-1530. doi: 10.1017/ice.2021.268.
Chow A, Htun HL, Kyaw WM, Ang H, Tan G, Tan HN, Koh LW, Thong BY, Ang B. Atypical COVID-19: Preventing transmission from unexpected cases. Infection control and hospital epidemiology. 2021 Sep;42(9):1146-1148. doi: 10.1017/ice.2020.419
Chow, B.W.K., Lim, Y.D., Poh, R.C.H. et al. Use of a digital contact tracing system in Singapore to mitigate COVID-19 spread. BMC Public Health 23, 2253 (2023). https://doi.org/10.1186/s12889-023-17150-0.
Choy, C. Y., & Wong, C. S. (2020). It's not all about COVID-19: Pneumocystis pneumonia in the era of a respiratory outbreak. Journal of the International AIDS Society, 23(6), e25533. https://doi.org/10.1002/jia2.25533.
Chye H, Chew CWY, Yeo HP, Tambyah PA, Young BE, Tan GGY, Tan BH, Vasoo S, Chan CEZ. Neutralization escape of emerging subvariants XBB.1.5/1.9.1 and XBB.2.3 from current therapeutic monoclonal antibodies. Journal of medical virology. 2023 Sep;95(9):e29074. doi: 10.1002/jmv.29074.
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Tan CW, Chia WN, Young BE, Zhu F, Lim BL, Sia WR, Thein TL, Chen MI, Leo YS, Lye DC, Wang LF. Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors. The New England journal of medicine. 2021 Oct 7;385(15):1401-1406.
Tan CW, Chia WN, Zhu F, Young BE, Chantasrisawad N, Hwa SH, Yeoh AY, Lim BL, Yap WC, Pada SKMS, Tan SY, Jantarabenjakul W, Toh LK, Chen S, Zhang J, Mah YY, Chen VC, Chen MI, Wacharapluesadee S, Sigal A, Putcharoen O, Lye DC, Wang LF. SARS-CoV-2 Omicron variant emerged under immune selection. Nat Microbiol. 2022 Nov;7(11):1756-1761. doi: 10.1038/s41564-022-01246-1
Tan CY, Chiew CJ, Lee VJ, Ong B, Lye DC, Tan KB. Effectiveness of a Fourth Dose of COVID-19 mRNA Vaccine Against Omicron Variant Among Elderly People in Singapore. Ann Intern Med. 2022 Nov;175(11):1622-1623. doi: 10.7326/M22-2042
Tan CY, Chiew CJ, Lee VJ, Ong B, Lye DC, Tan KB. Comparative effectiveness of 3 or 4 doses of mRNA and inactivated whole-virus vaccines against COVID-19 infection, hospitalization and severe outcomes among elderly in Singapore. Lancet Reg Health West Pac. 2022 Dec 2;29:100654. doi: 10.1016/j.lanwpc.2022.100654
Tan CY, Chiew CJ, Pang D, Lee VJ, Ong B, Lye DC, Tan KB. Vaccine effectiveness against Delta, Omicron BA.1, and BA.2 in a highly vaccinated Asian setting: a test-negative design study. Clin Microbiol Infect. 2023 Jan;29(1):101-106. doi: 10.1016/j.cmi.2022.08.002. Epub 2022 Aug 24
Tan CY, Chiew CJ, Pang D, Lee VJ, Ong B, Lye DC, Tan KB. Protective immunity of SARS-CoV-2 infection and vaccines against medically attended symptomatic omicron BA.4, BA.5, and XBB reinfections in Singapore: a national cohort study. Lancet Infect Dis. 2023 Jul;23(7):799-805. doi: 10.1016/S1473-3099(23)00060-9. Epub 2023 Mar 13.
Tan CY, Chiew CJ, Pang D, Lee VJ, Ong B, Wang LF, Ren EC, Lye DC, Tan KB. Effectiveness of bivalent mRNA vaccines against medically attended symptomatic SARS-CoV-2 infection and COVID-19-related hospital admission among SARS-CoV-2-naive and previously infected individuals: a retrospective cohort study. Lancet Infect Dis. 2023 Dec;23(12):1343-1348. doi: 10.1016/S1473-3099(23)00373-0. Epub 2023 Aug 2.
Tan GSE, Ding Y, Cui L, Mak TM, Mok CK, Kurup A, Parthasarathy P, Chia WN, Wang LF, Lin RTP, Leo YS, Vasoo S.Positive RT-PCR detected in patients recovered from COVID-19. Ann Acad Med Singap. 2021 Feb;50(2):191-194. https://doi.org/10.47102/annals-acadmedsg.2020387
Tan, G. P., Ho, S., Fan, B. E., Chotirmall, S. H., Tan, C. H., Lew, S. J. W., Chia, P. Y., Young, B. E., Abisheganaden, J. A., & Puah, S. H. (2020). Reversible platypnea-orthodeoxia in COVID-19 acute respiratory distress syndrome survivors. Respiratory Physiology & Neurobiology, 103515. https://doi.org/10.1016/j.resp.2020.103515
Tan GSE, Gao CQ, Ow JSY, Tan TT, Ooi ST, Lin C, Lin RTP, Lee VJM, Chan M, Leo YS, Vasoo S. Results from a systematic programme of evaluating COVID-19 reinfection cases in the early phase of the pandemic, Singapore. BMC Infect Dis. 2023 Feb 14;23(1):93. doi: 10.1186/s12879-023-08056-8
Tan, G. S. E., Hou, A., Manauis, C. M., Chua, J. M., Gao, C. Q., Ng, F. K. K., Wong, C. S., Ng, O.-T., Marimuthu, K., Chan, M., Leo, Y.-S., & Vasoo, S. (2020). Reducing hospital admissions for COVID-19 at a dedicated Screening Centre in Singapore. Clinical Microbiology and Infection, 0(0). https://doi.org/10.1016/j.cmi.2020.05.005
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Tan AT, Linster M, Tan CW, Le Bert N, Chia WN, Kunasegaran K, Zhuang Y, Tham CYL, Chia A, Smith GJD, Young B, Kalimuddin S, Low JGH, Lye D, Wang LF, Bertoletti A. Early induction of SARS-CoV-2 specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients. Cell Rep. 2021 Feb 9;34(6):108728. https://doi.org/10.1016/j.celrep.2021.10872
Tan EX, Lim WH, Thong E, Chavatte JM, Zhang J, Lim J, Jin JY, Lim DRX, Kang JYT, Tang ASP, Chan KE, Tan C, Tan SN, Nah B, Huang DQ, Wang LF, Tambyah PA, Somani J, Young B, Muthiah MD. Clinical Course, Immunogenicity, and Efficacy of BNT162b2 mRNA Vaccination Against SARS-CoV-2 Infection in Liver Transplant Recipients. Transplant Direct. 2023 Sep 20;9(10):e1537. doi: 10.1097/TXD.0000000000001537. eCollection 2023 Oct.
Tan KS, Ong SWX, Koh MH, Tay DJW, Aw DZH, Nah YW, Abdullah MRB, Coleman KK, Milton DK, Chu JJH, Chow VTK, Tambyah PA, Tham KW. SARS-CoV-2 Omicron variant shedding during respiratory activities. Int J Infect Dis. 2023 Jun;131:19-25. doi: 10.1016/j.ijid.2023.03.029. Epub 2023 Mar 21
Tan KYK, Soh ASE, Ong BWL, Chen MI, Griva K. Determining the Prevalence and Correlates of COVID-19 Booster Vaccine Hesitancy in the Singapore Population Following the Completion of the Primary Vaccination Series. Vaccines (Basel). 2022 Jul 6;10(7):1088. doi: 10.3390/vaccines10071088
Tan MW, Anelone AJN, Tay AT, Tan RY, Zeng K, Tan KB, Clapham HE. Differences in virus and immune dynamics for SARS-CoV-2 Delta and Omicron infections by age and vaccination histories. BMC Infect Dis. 2024 Jun 29;24(1):654. doi: 10.1186/s12879-024-09572-x.
Tan RY, Wong B, Lim R, Lee CL, Tan J, Tan KB, Wee LE. Factors associated with delayed diagnosis of symptomatic adult COVID-19 cases presenting to primary care: a population-wide study during transition from Delta to Omicron BA.1 in Singapore. Lancet Reg Health West Pac. 2023 Sep 27;41:100919. doi: 10.1016/j.lanwpc.2023.100919. eCollection 2023 Dec.
Tan TT, Ng HJ, Young B, Khan BA, Shetty V, Azmi N, Clissold S. Effectiveness of vaccination against SARS-CoV-2 and the need for alternative preventative approaches in immunocompromised individuals: a narrative review of systematic reviews. Expert Rev Vaccines. 2023 Jan-Dec;22(1):341-365. doi: 10.1080/14760584.2023.2191716
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Tan SHX, Cook AR, Heng D, Ong B, Lye DC, Tan KB. Effectiveness of BNT162b2 Vaccine against Omicron in Children 5 to 11 Years of Age. N Engl J Med. 2022 Aug 11;387(6):525-532. doi: 10.1056/NEJMoa2203209
Tan SHX, Pung R, Wang LF, Lye DC, Ong B, Cook AR, Tan KB. Association of Homologous and Heterologous Vaccine Boosters With COVID-19 Incidence and Severity in Singapore. JAMA. 2022 Mar 22;327(12):1181-1182. doi: 10.1001/jama.2022.1922.
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Tan V, Ang G, Tan KB, Chen C. Impact of COVID-19 national response on primary care utilisation in Singapore: an interrupted time-series analysis. Sci Rep. 2024 Mar 17;14(1):6408. doi: 10.1038/s41598-024-57142-7.
Tan WC, Tan JYJ, Lim JSJ, Tan RYC, Lee ARYB, Leong FL, Lee SC, Chai LYA, Tan TT, Malek MIBA, Ong B, Lye DC, Chiew CJ, Chng WJ, Lim ST, Bharwani LD, Tan IB, Sundar R, Tan KB. COVID-19 Severity and Waning Immunity After up to 4 mRNA Vaccine Doses in 73 608 Patients With Cancer and 621 475 Matched Controls in Singapore: A Nationwide Cohort Study. JAMA Oncol. 2023 Sep 1;9(9):1221-1229. doi: 10.1001/jamaoncol.2023.2271
Tan, W. Y. T., Wong, L. Y., Leo, Y. S., & Toh, M. P. H. S. (2020). Does incubation period of COVID-19 vary with age? A study of epidemiologically linked cases in Singapore. Epidemiology & Infection, 148. https://doi.org/10.1017/S0950268820001995
Tan, Wilnard Y. T., Young, B. E., Lye, D. C., Chew, D. E. K., & Dalan, R. (2020). Statin use is associated with lower disease severity in COVID-19 infection. Scientific Reports, 10(1), 17458. https://doi.org/10.1038/s41598-020-74492-0.
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Tat Ming Ng, Sock Hoon Tan, Shi Thong Heng, Hui Lin Tay, Min Yi Yap, Boon Hou Chua, Christine B Teng, David C Lye, Tau Hong Lee. Effects of coronavirus disease 2019 (COVID-19) pandemic on antimicrobial prevalence and prescribing in a tertiary hospital in Singapore. Antimicrob Resist Infect Control. 2021-12-01;10(1):1-8. doi: 10.1186/s13756-021-00898-8.
Tay EA, Vijayakumar V, Morales RF, Lee ES, Teo A. Protecting the endothelial glycocalyx in COVID-19. PLoS Pathog. 2024 May 16;20(5):e1012203. doi: 10.1371/journal.ppat.1012203. eCollection 2024 May.
Tay MZ, Ang LW, Wei WE, Lee VJM, Leo YS, Toh MPHS. Health-seeking behavior of COVID-19 cases during the first eight weeks of the outbreak in Singapore: differences between local community and imported cases and having visits to single or multiple healthcare providers. BMC Public Health. 2022 Feb 5;22(1):239. doi: https://doi.org/10.1186/s12889-022-12637-8.
Tay M, Lee B, Ismail MH, Yam J, Maliki D, Gin KY, Chae SR, Ho ZJM, Teoh YL, Ng LC, Wong JCC. Usefulness of aircraft and airport wastewater for monitoring multiple pathogens including SARS-CoV-2 variants. J Travel Med. 2024 Jul 7;31(5):taae074. doi: 10.1093/jtm/taae074.
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Umapathi T, Li KZ, Chin CF, Vijakumar K, Tan GSE, Ung PH, Yeo TK, Agrawal R. Acute Isolated Near Vision Difficulty in Patients With COVID-19 Infection. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2021 Sep 1;41(3):e279-e282. doi: 10.1097/WNO.0000000000001120
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Wang SSY, Chee K, Wong SW, Tan GB, Ang H, Leung BP, Tan CW, Ramanathan K, Dalan R, Cheung C, Lye DC, Young BE, Yap ES, Chia YW, Fan BE; COVID-19 Clotting and Bleeding Investigators. Increased Platelet Activation demonstrated by Elevated CD36 and P-Selectin Expression in 1-Year Post-Recovered COVID-19 Patients. Semin Thromb Hemost. 2023 Jul;49(5):561-564. doi: 10.1055/s-0043-1762578. Epub 2023 Feb 13
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